An experimental biology and bioinformatics laboratory studying the principles of 3D genome folding in cancer.

Welcome to the 3D Chromatin Organisation Laboratory at SAiGENCI

TThe 3D Chromatin Organisation Laboratory, led by Dr Joanna Achinger-Kawecka, investigates the regulatory principles of three-dimensional (3D) genome folding and transcriptional control. This 3D organisation of the genome brings together genes and distal regulatory elements to orchestrate gene transcription, and has been implicated in many diseases, including cancer.

Our lab develops new genomics technologies and bioinformatics approaches to explore the role of 3D chromatin organisation in driving cancer progression and treatment resistance. Understanding this oncogenic role of the 3D regulatory genome will accelerate the development of new targeted therapeutic interventions for cancer.